Before having a colonoscopy, patients have to go through the process of flushing out their bowels. However, new information indicating that this may be the most dangerous part of the procedure, as the drugs products that assist in the flushing may pose a risk of acute kidney injury.
The Food and Drug Administration has mandated Salix Pharmaceuticals Ltd., the manufacturer of two of the most commonly used prescription flushing products, Visicol and OsmoPrep, to put a "black box" warning on its labels. A "black box" warning is the most severe warning that the FDA issues on prescription medications. The agency further directed the drug manufacturer to conduct a clinical trial to specifically assess the risk of the products, especially to the kidneys.
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Black Box Warning added on Visicol and OsmoPrep for Effects on Kidneys
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